Details for gene set NCI_IL1-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_01_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos
Phenotype	phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos
Upregulated in class	ATM_plus
GeneSet	NCI_IL1-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.46764788
Normalized Enrichment Score (NES)	-1.8828572
Nominal p-value	0.0
FDR q-value	0.021827882
FWER p-Value	0.227

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CEBPB	1418901_at 1427844_a_at	98	7.620	0.0184	No
2	FGR	1419526_at 1442804_at	204	5.919	0.0313	No
3	FYN	1417558_at 1441647_at 1448765_at	519	4.286	0.0298	No
4	CDK4	1422441_x_at	544	4.192	0.0412	No
5	BLK	1422775_at	610	3.996	0.0503	No
6	XPO1	1418442_at 1418443_at 1448070_at	1151	2.956	0.0343	No
7	ATF1	1417296_at	1483	2.611	0.0269	No
8	MALT1	1445068_at 1456126_at 1456429_at	1490	2.604	0.0345	No
9	MAPKAPK2	1426648_at	1668	2.413	0.0336	No
10	ELK4	1422233_at 1427162_a_at 1447571_at 1450549_s_at	1694	2.393	0.0396	No
11	KPNB1	1416925_at 1434357_a_at 1448526_at 1451967_x_at	1733	2.357	0.0449	No
12	MAF	1435828_at 1437473_at 1444073_at 1447849_s_at 1447945_at 1456060_at	1970	2.170	0.0406	No
13	PPARG	1420715_a_at	2038	2.118	0.0439	No
14	IL2RA	1420691_at 1420692_at	2087	2.083	0.0479	No
15	TCF3	1436207_at 1450117_at	2124	2.060	0.0525	No
16	FOSL1	1417487_at 1417488_at	2333	1.933	0.0487	No
17	RIPK1	1419508_at 1439273_at 1449485_at	2512	1.830	0.0460	No
18	E2F1	1417878_at 1431875_a_at 1447840_x_at	2542	1.816	0.0501	No
19	SLC3A2	1425364_a_at	2914	1.676	0.0381	No
20	TP53	1426538_a_at 1427739_a_at 1438808_at 1457623_x_at 1459780_at 1459781_x_at	3061	1.619	0.0363	No
21	RPS6KA4	1438243_at 1448498_at	3178	1.576	0.0357	No
22	PRKCI	1417410_s_at 1448695_at	3408	1.506	0.0297	No
23	MAP3K14	1422999_at 1434364_at	3434	1.499	0.0330	No
24	YWHAG	1420816_at 1420817_at 1450012_x_at 1459693_x_at	3489	1.477	0.0350	No
25	MEF2A	1421252_a_at 1425426_a_at 1427185_at 1427186_a_at 1452347_at	3764	1.390	0.0265	No
26	CASP3	1426165_a_at 1430192_at 1449839_at	3970	1.341	0.0211	No
27	IRAK4	1421670_a_at 1451749_at	4345	1.260	0.0077	No
28	CALM3	1426710_at 1438825_at 1438826_x_at 1450864_at	4358	1.257	0.0110	No
29	EGR4	1449977_at	4461	1.237	0.0100	No
30	RNF128	1418318_at 1449036_at	4517	1.228	0.0111	No
31	MAP3K7IP1	1426898_at 1447692_x_at	4524	1.228	0.0146	No
32	MKNK1	1417630_at 1417631_at 1454119_at	4646	1.202	0.0126	No
33	SQSTM1	1440076_at 1442237_at 1444021_at 1450957_a_at	4868	1.159	0.0059	No
34	CALM2	1422414_a_at 1423807_a_at	5136	1.110	-0.0030	No
35	YWHAB	1420878_a_at 1420879_a_at 1420880_a_at 1436783_x_at 1438708_x_at 1455815_a_at	5228	1.094	-0.0039	No
36	USF1	1426164_a_at 1448805_at 1459758_at	5269	1.087	-0.0025	No
37	MAP3K7	1419988_at 1425795_a_at 1426627_at 1449693_at 1455441_at 1458787_at	5318	1.078	-0.0015	No
38	IFNG	1425947_at	5363	1.070	-0.0003	No
39	PRKG1	1443663_at 1443811_at 1443812_x_at 1444232_at 1445807_at 1445998_at 1449876_at	5772	1.013	-0.0160	No
40	DUSP8	1418714_at	5804	1.009	-0.0144	No
41	EIF4EBP1	1417562_at 1417563_at 1434976_x_at	5828	1.006	-0.0124	No
42	RAN	1443131_at 1446819_at 1447478_at 1460551_at	5842	1.004	-0.0100	No
43	UBE2D3	1423112_at 1423113_a_at 1423114_at 1450858_a_at 1450859_s_at 1455479_a_at 1455480_s_at	5934	0.995	-0.0112	No
44	IRAK3	1430704_at 1435040_at	6005	0.986	-0.0115	No
45	PRKCZ	1418085_at 1449692_at 1454902_at	6548	0.906	-0.0337	No
46	IL3	1450566_at	7697	0.750	-0.0842	No
47	IRAK1	1448668_a_at 1460649_at	7836	0.731	-0.0883	No
48	BAD	1416582_a_at 1416583_at	8047	0.703	-0.0959	No
49	RAC1	1423734_at 1437674_at 1451086_s_at	8062	0.701	-0.0944	No
50	MEF2C	1421027_a_at 1421028_a_at 1424852_at 1439946_at 1445420_at 1446484_at 1451506_at 1451507_at 1458551_at	8419	0.655	-0.1088	No
51	MAPK14	1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at	9038	0.581	-0.1355	No
52	TBX21	1449361_at	9537	0.523	-0.1568	No
53	CASP1	1449265_at	9683	0.506	-0.1620	No
54	YWHAZ	1416102_at 1416103_at 1436971_x_at 1436981_a_at 1439005_x_at 1443893_at 1448218_s_at 1448219_a_at	9868	0.485	-0.1690	No
55	CYLD	1429617_at 1429618_at 1445213_at	10365	0.433	-0.1905	No
56	ETV1	1422607_at 1445314_at 1450684_at	10374	0.431	-0.1895	No
57	IL4	1449864_at	10496	0.418	-0.1938	No
58	TH	1420546_at	10507	0.417	-0.1931	No
59	AKAP5	1447301_at	11001	0.361	-0.2146	No
60	CSF2	1427429_at	11147	0.346	-0.2203	No
61	RPS6KA5	1431050_at 1437625_at 1439004_at 1440343_at	11230	0.336	-0.2230	No
62	RIPK2	1421236_at 1450173_at	11319	0.326	-0.2261	No
63	SYK	1418261_at 1418262_at 1425797_a_at 1457239_at	11646	0.289	-0.2402	No
64	TNF	1419607_at	11771	0.274	-0.2451	No
65	YWHAQ	1420828_s_at 1420829_a_at 1420830_x_at 1432842_s_at 1437608_x_at 1454378_at 1460590_s_at 1460621_x_at	12338	0.217	-0.2705	No
66	SRC	1423240_at 1450918_s_at	12634	0.185	-0.2835	No
67	MAP2K3	1425456_a_at 1451714_a_at	12651	0.183	-0.2837	No
68	IL1RN	1423017_a_at 1425663_at 1451798_at	12787	0.166	-0.2894	No
69	MYD88	1419272_at	12976	0.145	-0.2976	No
70	MAPK8	1420931_at 1420932_at 1437045_at 1440856_at 1457936_at	13226	0.116	-0.3087	No
71	JUN	1417409_at 1448694_at	13265	0.110	-0.3101	No
72	PPARGC1A	1434099_at 1434100_x_at 1437751_at 1456395_at 1460336_at	13278	0.108	-0.3103	No
73	PTGS2	1417262_at 1417263_at	13435	0.089	-0.3172	No
74	PLA2G4A	1448558_a_at	13525	0.078	-0.3211	No
75	MAP3K3	1426686_s_at 1426687_at 1436522_at	13720	0.051	-0.3299	No
76	IL1B	1449399_a_at	13777	0.043	-0.3323	No
77	CDC25B	1421963_a_at	13819	0.038	-0.3341	No
78	YES1	1418470_at 1449090_a_at 1456843_at 1458878_at	14075	0.006	-0.3458	No
79	ESR1	1421244_at 1435663_at 1457877_at 1460591_at	14124	-0.002	-0.3480	No
80	PAK3	1417923_at 1417924_at 1437318_at	14191	-0.013	-0.3510	No
81	SFN	1448612_at	14234	-0.019	-0.3528	No
82	PTPRK	1423277_at 1423278_at 1431680_a_at 1441276_at 1441277_s_at 1441644_at 1443491_at 1443699_at 1444763_at	14337	-0.034	-0.3574	No
83	TRAF6	1421376_at 1421377_at 1435350_at 1443288_at 1446940_at 1446977_at	14353	-0.036	-0.3580	No
84	IL1R2	1419532_at 1457108_at	14476	-0.054	-0.3635	No
85	IL1A	1421473_at	14640	-0.081	-0.3707	No
86	PIK3CA	1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at	14972	-0.133	-0.3855	No
87	PRKCE	1437860_at 1437861_s_at 1442609_at 1444649_at 1449956_at 1452878_at	15005	-0.138	-0.3866	No
88	ATM	1421205_at 1428830_at	15042	-0.145	-0.3878	No
89	PIK3R1	1425514_at 1425515_at 1438682_at 1444591_at 1451737_at	15248	-0.177	-0.3967	No
90	MAPK11	1421925_at 1421926_at	15750	-0.271	-0.4189	No
91	PIM1	1423006_at 1435458_at	15787	-0.279	-0.4197	No
92	PRKCA	1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at	15983	-0.319	-0.4277	No
93	FKBP1A	1416036_at 1438795_x_at 1438958_x_at 1448184_at 1456196_x_at	16008	-0.325	-0.4279	No
94	IL1R1	1448950_at 1459777_at	16020	-0.328	-0.4274	No
95	IRF4	1421173_at 1421174_at	16277	-0.392	-0.4380	No
96	CD40LG	1422283_at	16403	-0.421	-0.4425	No
97	REL	1420710_at	16635	-0.480	-0.4517	No
98	HCK	1446553_at 1449455_at	16712	-0.502	-0.4536	No
99	NFATC1	1417621_at 1425761_a_at 1428479_at 1447084_at 1447085_s_at	16786	-0.526	-0.4554	No
100	PRKACA	1447720_x_at 1450519_a_at	16824	-0.536	-0.4555	No
101	FOXP3	1420765_a_at 1457082_at	17059	-0.612	-0.4644	No
102	PTPN1	1417068_a_at 1438670_at	17061	-0.612	-0.4626	No
103	FASLG	1418803_a_at 1449235_at	17094	-0.623	-0.4622	No
104	IKBKB	1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at	17210	-0.664	-0.4655	Yes
105	CREB1	1421582_a_at 1421583_at 1423402_at 1428755_at 1452529_a_at 1452901_at	17226	-0.671	-0.4642	Yes
106	RAF1	1416078_s_at 1425419_a_at	17235	-0.675	-0.4625	Yes
107	DUSP16	1418401_a_at 1440615_at 1440651_at	17261	-0.683	-0.4616	Yes
108	ERC1	1421501_a_at 1424247_at 1441493_at 1444356_at 1451279_at	17322	-0.702	-0.4623	Yes
109	EIF4E	1450909_at 1457489_at 1459371_at	17356	-0.717	-0.4617	Yes
110	FBXW11	1425461_at 1425462_at 1437468_x_at 1438336_at 1443010_at 1447294_at 1457485_at	17437	-0.752	-0.4631	Yes
111	TOLLIP	1423047_at 1423048_a_at	17480	-0.771	-0.4627	Yes
112	CALM1	1417365_a_at 1417366_s_at 1433592_at 1454611_a_at 1455571_x_at	17505	-0.779	-0.4615	Yes
113	POU2F1	1419716_a_at 1427695_a_at 1427835_at	17578	-0.808	-0.4623	Yes
114	MITF	1422025_at 1455214_at	17602	-0.821	-0.4609	Yes
115	TSC2	1452105_a_at	17608	-0.823	-0.4587	Yes
116	MAP2K4	1426233_at 1442679_at 1451982_at	17730	-0.871	-0.4616	Yes
117	MAPK9	1421876_at 1421877_at 1421878_at	17782	-0.895	-0.4613	Yes
118	CHUK	1417091_at 1428210_s_at 1451383_a_at	17804	-0.903	-0.4596	Yes
119	CSNK1A1	1424827_a_at 1428537_at 1430529_at 1451497_at 1456216_at	17814	-0.908	-0.4572	Yes
120	ARRB2	1426239_s_at 1451987_at	17849	-0.929	-0.4560	Yes
121	MEF2D	1421388_at 1434487_at 1436642_x_at 1437300_at 1458901_at	17877	-0.936	-0.4544	Yes
122	MAP2K6	1426850_a_at 1459292_at	17943	-0.963	-0.4545	Yes
123	NFKBIA	1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at	18087	-1.008	-0.4581	Yes
124	CAMK4	1421941_at 1426167_a_at 1439843_at 1442822_at 1452572_at	18098	-1.010	-0.4555	Yes
125	FKBP8	1416113_at	18186	-1.035	-0.4564	Yes
126	UBE2N	1422559_at 1435384_at	18407	-1.125	-0.4631	Yes
127	MAPKAPK5	1417016_at 1439828_at	18426	-1.132	-0.4606	Yes
128	ATF6	1435444_at 1453288_at 1456021_at	18499	-1.169	-0.4604	Yes
129	NUP214	1434351_at 1456503_at 1457815_at	18505	-1.172	-0.4571	Yes
130	NFKB2	1425902_a_at 1429128_x_at	18571	-1.202	-0.4565	Yes
131	RAB5A	1416426_at 1446129_at	18602	-1.214	-0.4542	Yes
132	MAP3K8	1419208_at	18698	-1.260	-0.4548	Yes
133	HSPB1	1422943_a_at 1425964_x_at 1427853_a_at 1427854_x_at 1453914_at	18931	-1.393	-0.4613	Yes
134	LCK	1425396_a_at 1439145_at 1439146_s_at 1457917_at	19071	-1.481	-0.4632	Yes
135	DUSP10	1417163_at 1417164_at	19106	-1.503	-0.4602	Yes
136	RALB	1417744_a_at 1435517_x_at	19134	-1.522	-0.4569	Yes
137	SRF	1418255_s_at 1418256_at	19149	-1.533	-0.4530	Yes
138	SLC9A1	1417397_at	19217	-1.578	-0.4513	Yes
139	CCM2	1434648_a_at 1434649_at 1456290_x_at 1457339_at	19347	-1.662	-0.4522	Yes
140	MAPK3	1427060_at	19380	-1.691	-0.4486	Yes
141	IL5	1425546_a_at 1442049_at 1450550_at	19394	-1.700	-0.4441	Yes
142	MAP3K12	1417115_at 1438908_at 1456565_s_at	19465	-1.743	-0.4421	Yes
143	PRKCH	1422079_at 1434248_at	19474	-1.756	-0.4372	Yes
144	NFATC2	1425901_at 1425990_a_at 1426031_a_at 1426032_at 1439205_at 1440426_at	19581	-1.851	-0.4365	Yes
145	IKBKG	1421208_at 1421209_s_at 1435646_at 1435647_at 1450161_at 1454690_at	19699	-1.951	-0.4360	Yes
146	YWHAE	1426384_a_at 1426385_x_at 1435702_s_at 1438839_a_at 1440841_at 1457173_at	19732	-1.981	-0.4316	Yes
147	PAK1	1420979_at 1420980_at 1450070_s_at 1459029_at	19738	-1.986	-0.4258	Yes
148	BCL10	1418970_a_at 1418971_x_at 1418972_at 1443524_x_at	19756	-1.997	-0.4206	Yes
149	HBP1	1432143_a_at 1438430_at 1446269_at 1460367_at	19815	-2.032	-0.4172	Yes
150	TMED7	1419917_s_at 1419918_at 1427314_at 1427315_at 1429187_at	19837	-2.044	-0.4120	Yes
151	RALA	1423137_at 1450870_at 1456049_at	19898	-2.087	-0.4085	Yes
152	ATF2	1426582_at 1426583_at 1427559_a_at 1437777_at 1452116_s_at 1459237_at	19925	-2.103	-0.4034	Yes
153	CBLB	1437304_at 1455082_at 1458469_at	19947	-2.123	-0.3980	Yes
154	MAPKAPK3	1434815_a_at 1437494_at	19978	-2.157	-0.3929	Yes
155	YWHAH	1416004_at	20026	-2.200	-0.3884	Yes
156	ITCH	1415769_at 1431316_at 1459332_at	20078	-2.248	-0.3840	Yes
157	CTLA4	1419334_at	20241	-2.409	-0.3842	Yes
158	NFKB1	1427705_a_at 1442949_at	20346	-2.528	-0.3814	Yes
159	BCL3	1418133_at	20382	-2.577	-0.3753	Yes
160	DDIT3	1417516_at 1443897_at	20440	-2.645	-0.3700	Yes
161	GATA3	1448886_at	20751	-3.097	-0.3749	Yes
162	RELA	1419536_a_at	20799	-3.184	-0.3675	Yes
163	MAP3K7IP2	1423462_at 1451003_at	20887	-3.362	-0.3614	Yes
164	PAK2	1434250_at 1454887_at	20929	-3.442	-0.3530	Yes
165	FOS	1423100_at	20955	-3.496	-0.3436	Yes
166	EP300	1434765_at	20959	-3.504	-0.3332	Yes
167	BIRC2	1418854_at	21087	-3.757	-0.3278	Yes
168	TNFAIP3	1433699_at 1450829_at	21180	-3.976	-0.3201	Yes
169	CREBBP	1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at	21224	-4.102	-0.3097	Yes
170	BCL2	1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at	21309	-4.363	-0.3005	Yes
171	RELB	1417856_at	21351	-4.570	-0.2887	Yes
172	PRKCQ	1426044_a_at	21404	-4.723	-0.2769	Yes
173	DUSP1	1448830_at	21461	-4.952	-0.2646	Yes
174	JUNB	1415899_at	21503	-5.184	-0.2509	Yes
175	NR4A1	1416505_at	21561	-5.542	-0.2369	Yes
176	MAP3K1	1424850_at	21563	-5.558	-0.2202	Yes
177	GDI1	1447613_at 1451070_at	21575	-5.645	-0.2038	Yes
178	TNFRSF1A	1417291_at	21597	-5.736	-0.1875	Yes
179	NFATC3	1419976_s_at 1452497_a_at	21671	-6.290	-0.1720	Yes
180	PRKCD	1422847_a_at 1442256_at	21741	-6.917	-0.1544	Yes
181	DGKA	1418578_at	21744	-6.953	-0.1336	Yes
182	CSNK2A1	1419034_at 1419035_s_at 1419036_at 1419037_at 1419038_a_at 1453427_at	21816	-7.560	-0.1141	Yes
183	LSP1	1417756_a_at	21836	-7.735	-0.0918	Yes
184	EGR1	1417065_at	21860	-7.832	-0.0693	Yes
185	GSK3B	1434439_at 1437001_at 1439931_at 1439949_at 1451020_at 1454958_at	21861	-7.833	-0.0458	Yes
186	EGR2	1427682_a_at 1427683_at	21904	-8.113	-0.0234	Yes
187	EGR3	1421486_at 1436329_at	21913	-8.258	0.0011	Yes